The term multi-domain operations (MDO) encompasses the traditional physical domains as well as the rapidly expanding domains of space and cyber. It strives for selective interdependence and integration between services, down till the tactical level. Achieving information superiority and decision dominance through cross-domain application, synergy and tempo are central to successful MDO. Aerospace power’s intrinsic attributes, doctrinal percepts, actual combat experience of cross-domain operations and proficiency in network-centric operations resonate well with MDO.