The rapid developments in science and technology are opening new frontlines for policy priorities in biosecurity. Science and technology are also at the central to the Biological Weapons Convention. The present policy and regulatory frameworks, both at national and multilateral levels, are insufficient for managing the changes in science and technology and the concomitant opportunities and challenges they create. Policy institutions should frequently involve scientists having varied expertise to understand and develop policy expositions based on the latest scientific developments and their possible influence. Here, technology foretelling and anticipatory science policy tools could be applied, particularly for the convergence of emerging technologies.