Global leaders have discovered from COVID-19 that we cannot overlook the threats from infectious disease. One such impending threat is and which may have global repercussions is Antimicrobial Resistance. As per the securitization model, for an existential threat to become a security issue, it needs to have a speech act followed by a receptive audience and ultimately, a policy-driven solution by the government. Finding inadequacy of securitization theory, the concept of macro-securitization was introduced by the same author to understand the phenomenon.