It is difficult to escape the conclusion that two decades have been wasted due to the persistent weakness of a crucial component of the Web of Prevention-the Biological and Toxin Weapons Convention (BTWC). Furthermore, with the destruction of chemical weapons now complete, it is evident that both the Chemical Weapons Convention (CWC) and the BTWC face the shared challenge of preventing the resurgence of these weapon systems. They are also inherently connected in addressing the threat posed by toxin and bio-regulatory weapons. Although a rapid strengthening of the BTWC seems unlikely at present, when the opportunity arises, it will likely require adopting key mechanisms such as declarations, visits, and inspections, similar to those of the CWC, to ensure its effectiveness.